BioSolvetIT SeeSAR 14.1.2

BioSolvetIT SeeSAR 14.1.2​
File size: 356.3 MB​

SeeSAR is your intuitive, visual drug design platform. Covering every step of your drug discovery process – from virtual screening to fragment-based design – SeeSAR fosters ideation in the most fun and comprehensive way.

SeeSAR fosters innovation during every step of your drug design process. The app includes all tools vital for handling your compounds and target structures which have been fine-tuned to the needs of any chemist.
Helpful features such as ADME properties assessment, comprehensive color coding, unoccupied binding pocket visualization, and many others, support you in making sound and interactive decisions.
All our tools are based on solid and transparent science cited in over a thousand publications. Follow the button if you want to learn more about the science behind SeeSAR.

fast
Dock, design, and analyze your compound in a flash, with swift and informative calculations.

visual
Evaluate ligand-target interactions by intuitive color codes and gorgeous visualization.

easy
We provide a satisfying on-the-fly drug design experience. No learning curve!

Protein Mode
Drag and drop your protein, or search comfortably in an online database. Within seconds, your target is prepared and you can get started.

Protein Editor Mode
Modify your protein according to your needs. Explore rotamers, introduce mutations, and customize side chains.
binding site mode for target pocket detection

Binding Site Mode
SeeSAR automatically detects the binding site of a ligand for you. In addition, you can precisely expand it by adding individual residues – or with a single click to find empty pockets in your protein.
molecule editor mode for on-the-fly modifications of your compounds

Molecule Editor Mode
Modify molecules to your taste in 2D or 3D on-the-fly. Once you are done, the molecules are directly prepared for your tasks.

analyzer mode for property assessment
Estimate affinities and interpret the results using the visualized HYDE score. Filter your compounds for relevant parameters, calculate ADME properties, and gain full control over ligand-target interactions.

inspirator mode for interesting new structural proposals
Ideate without limits! Discover new scaffolds, explore, and grow into free cavities, or link molecules using fragment libraries for elegant solutions.

docking mode for binding mode predictions
Dock your compounds with one single click! Screen libraries for actives, and instinctively evaluate your results.

Similarity Scanner Mode
Align your compounds without the need of a target structure based on their molecular similarity.

System Requirements
-RAM: 8GB would be good, anything beyond is better.
-CPU: Our tools are not very hungry – yet they profit from multiple CPUs, because they have parallelized algorithms implemented. If in doubt rather choose more slower CPUs than one faster one.
-Graphics: It is important to know that a local graphics card is mandatory for infiniSee and SeeSAR.

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https://www.biosolveit.de/SeeSAR/changelog/

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BioSolvetIT SeeSAR 14.1.2 (356.32 MB)

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BioPharmics Surflex Platform 5.197 MultiOS

File size: 2.4 GB​

The Surflex Platform consists of the five modules described below. The Surflex Manual contains details of all computational procedures and options within each command-line module. We support Linux (most common variants), Windows, and MacOS. All of the modules are multi-core capable, and very substantial speed-ups are observed with modern multi-core laptops, workstations, and HPC clusters.

Tools Module
Fast and Accurate Small Molecule Processing

The Tools module addresses the most common aspects of small-molecule preparation
2D to 3D conversion (from SMILES or SDF)
Chirality detection and enumeration
Protonation
Conformer generation

Features and benefits
Template-free and non-stochastic
Relies on MMFF94sf forcefield for structure derivation
Fast and accurate on typical drug-like ligands, with better coverage of diverse conformations
Fastest and most accurate method for macrocyclic ligands
Capable of incorporating NMR restraints, which is particularly useful for large peptidic macrocycles

Similarity Module
State-of-the-Art 3D Molecular Similarity

The Similarity module implements ligand similarity operations using the eSim method
Virtual screening
Pose prediction
Multiple ligand alignment
The core eSim methodology is also integrated into the Docking and QuanSA modules.

Features and benefits
Virtual screening enrichment is both practically and statistically significantly better than alternative methods
Virtual screening speeds of over 20 million compounds per day on a single computing core
Databases of billions of molecules can be screened in hours using cloud-based computing resources
Pose prediction accuracy is substantially better than alternative approaches

Docking and xGen Modules
Top-Tier Solution for Virtual Screening and pose Prediction + Real-Space X-ray Density Modeling of Ligands

The Docking module addresses all aspects of ensemble docking
Large-scale PDB retrieval and processing
Surface-based binding site alignment using the PSIM method
Fully automatic pocket variant selection to cover the relevant protein conformational variation
Virtual screening
Pose prediction

Feature and benefits
Automated alignment and selection of appropriate binding site variants
Robust and fully automatic modes for virtual screening and pose prediction\Very extensive validation
Highly accurate non-cognate ligand docking
Directly applicable to synthetic macrocycles, with accuracy equivalent to non-macrocycles
The xGen module implements a novel method for real-space refinement and de novo fitting of ligand ensembles into X-ray density maps

Models ligand density using conformational ensembles
Avoids atom-specific B-factors as X-ray model parameters
Produces chemically sensible conformers with low strain energy; applicable to complex macrocycles
Yields superior fit to X-ray density than standard fitting approaches
Accessible to non-crystallographers and as part of crystallographic workflows

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https://www.biopharmics.com/Public/RELEASE.txt

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https://optibrium.com/products/product-installation/biopharmics/

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BioPharmics Surflex Platform 5.197 MultiOS (2.46 GB)

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Binary Ninja v5.1.8104 Portable by FC – (425 MB)

Binary Ninja v5.1.8104​

Binary Ninja is an interactive disassembler, decompiler, and binary analysis platform for reverse engineers, malware analysts, vulnerability researchers, and software developers that runs on Windows.

Disassemble Files
Vector 35 provides first-party support for dissassembly from multiple architectures, including x86, x86-64, ARMv7 (with Thumb2), ARMv8 (AArch64), PowerPC, 6502, Z80, and MIPS. Additionally, our community supports many other architectures through our public plugin ecosystem. Loaders are available for all major platforms (PE, Mach-O, ELF) and can be extended or customized using our API.

Decompile Code
Our built-in decompiler works with all of our officially supported architectures at one price and builds on a powerful family of ILs called BNIL. In fact, not just our architectures, but even community architectures can produce amazing decompilation. Our decompiler outputs to both C and BNIL and can be switched on-demand.

Automate Anything
Our extensive API can be used to create and customize loaders, add or augment architectures, customize the UI, or automate any workflow (types, patches, decompilation.anything!). Bindings are available for C++, Python, and Rust.

Create Plugins
Made something cool and want to share? Publish your community plugin and have it featured in our Plugin Manager! These plugins can be installed (or updated) at any time by any customer, right inside the client.

Triage Quickly
Use our API to quickly batch process files and see the results in our triage view. Use the entropy graph to identify areas of interest, like packed or encrypted data. Click on any location to navigate there quickly.

Explore Interactively
We didn’t just build the best automation and API for binary analysis, but our UI design is intentional and clean. None of the distractions, but all of the features you need for the biggest jobs including multiple tabs, synchronized and split views, custom layouts and more.

Annotate Everything
Reverse engineering is the process of exploring the unknown. As your understanding improves, we give you the tools to represent that and improve analysis. Add types, structures, comments, highlights, tags, and more.

Patch Effectively
Make binary patches quickly and effectively with a variety of tools purpose-built for speed. Edit lines of assembly directly, select a preset patch, edit raw bytes with our hex editor view, or even compile C into the executable directly with our own built in compiler SCC.

Switch Platforms

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https://binary.ninja/changelog/

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Binary Ninja v5.1.8104 Portable by FC – (425 MB)
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BIMIZE WorksetFinder Select All In A Workset! 2025 2026 3.1.0

File size: 3.0 MB​

Now you can find all elements that are within a project workset and select them all at once. You can also choose types or instances. Just follow the steps!

(1) Select the workset you want to select items from,
(2) Choose whether to select types or instances.
Great for coordination and project BIM Managers.

Compatible with
Autodesk Revit version: 2026, 2025

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https://apps.autodesk.com/RVT/en/Detail/Index?id=5333756268899711203&appLang=en&os=Win64

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BIMIZE WorksetFinder Select All In A Workset! 2025 2026 3.1.0 (2.78 MB)

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Bimize Linkreloader Reload Multiple At Once! 2025 2026 V5.1.0

Bimize Linkreloader Reload Multiple At Once! 2025 2026 V5.1.0​
File size: 1 MB​

Save time by reloading all Autodesk® Revit® links in a document by using Link Reloader. With this batch tool, you don’t even need to open the document to reload any desired links.

Just follow the steps!
(1) Select the main Revit project where links or references need to be reloaded
(2) Select the computer folder where the Revit links are saved

Great for coordination and team sharing! Have you ever received an E-Transmitted file with tons of links to reload? Do you lose an insane amount of time having to reload your attached docs? No worries anymore, we are here to help!

Note: Works without having to open a document.

Compatible with
Autodesk Revit
Version: 2026, 2025

Whats New
Updates: official site does not provide any info about changes in this version

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Bimize Linkreloader Reload Multiple At Once! 2025 2026 V5.1.0 (769.56 KB)
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BIMIZE AutoExcel One Click Excel Link! 2025 2026 7.3.0

File size: 3.0 MB​

With Auto Excel, you will be able to quickly export and re-import any Autodesk® Revit® project schedule to Microsoft® Excel®. The best batch tool to modify lots of parameters at once.

(1) Open any project schedule and click "export"
(2) Modify the Excel generated file
(3) Go back to the same project schedule and click on "import"
Great for the modification of tons of parameters in a single step. Use Excel to organize your data and parameters!

Compatible with
Autodesk Revit version: 2026, 2025

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https://apps.autodesk.com/RVT/de/Detail/Index?id=5444551143944045781&appLang=en&os=Win64

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BIMIZE AutoExcel One Click Excel Link! 2025 2026 7.3.0 (2.49 MB)

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Omni Loop (2024) [1080p] [WEB] [x265] [5.1]

Omni Loop (2024) 5.6 (3,348 Votes)
Runtime: 1h 52m

Genre: Drama, Sci-Fi

Cast: Mary-Louise Parker, Ayo Edebiri, Carlos Jacott

Plot: A woman from Miami, Florida decides to solve time travel in order to go back and be the person she always intended to.

Omni.Loop.2024.1080p.10bit.WEBRip.6CH.x265.HEVC-PSA

IMDb INFO
Omni Loop
2024 • 1h 47m
Drama • Sci-Fi

A woman from Miami, Florida decides to solve time travel in order to go back and be the person she always intended to.

Director: Bernardo Britto
Writer: Bernardo Britto
Stars: Mary-Louise Parker • Ayo Edebiri • Carlos Jacott Click to expand…
FURTHER INFO
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https://www.imdb.com/title/tt28150132/
https://www.themoviedb.org/movie/1143128

FILE INFO
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GENERAL.....: Matroska | 1.75 GiB | 1 h 51 min | 2252 kb/s
VIDEO.......: HEVC (10 bits) | 2074 kb/s | 1920x800 | 2.40:1 | 23.976 FPS
AUDIO.......: AAC LC SBR | 176 kb/s | 6 channels | English
SUBTITLES...: English | English SDH
SOURCE......: Omni.Loop.2024.1080p.AMZN.WEB-DL.DDP5.1.H.264-FLUX

SCREENSHOTS

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▼ MOVIE COLLECTIONS ▼ (102 Threads, 616 Movies)
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▼ COMPLETE SERIES ▼
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BIM CONSULT BIMida 1.3.3

BIM CONSULT BIMida 1.3.3​
File size: 25.2 MB​

BIMida is primarily intended for BIM projects in Luxembourg and Belgium, aiming to comply with national data frameworks (GID sheets).

These GID sheets are available on the website www.bimids.eu. It is particularly useful during BIM tenders or contracts that define required information levels for each phase and use case (e.g., CRTI-B/Buildwise conventions). Internally, BIM Managers and modelers can use BIMida to ensure all required data is filled before deliverables are submitted, avoiding omissions and non-compliance.

By unifying the property entry format, the plugin also simplifies model exchanges between stakeholders and prepares a clean IFC export with the correct properties in the right places.

Lastly, BIMida evolves alongside standards: new use cases and data requirements can be added in future updates. The current version already supports a broad range (regulatory, analysis, maintenance, etc.) and serves as an operational reference for implementing the Level of Information Need in Autodesk® Revit®. In short, BIMida is an essential BIM data maintenance tool for keeping models aligned with established requirements and facilitating information exchange throughout the project lifecycle.

Compatible with
Autodesk Revit
Version: 2026 , 2025 , 2024 , 2023

Whats New
Updates: official site does not provide any info about changes in this version

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BIM CONSULT BIMida 1.3.3 (25.23 MB)
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Beyond Sync 7.5.60.1394 Multilingual

Beyond Sync 7.5.60.1394 Multilingual​
File size: 7.9 MB​

Real time sync monitors folders and start sync as soon as there are files were created, updated or deleted. It’s the easiest and the most effective solution you can find for a file sync product. It doesn’t scan folder at all, this means it almost doesn’t use CPU and memory resource. It also means real time sync always has same and the best performance no matter you have one hundred or one million files.

Block Level Sync
Only copy changed part when a file is updated. It improves the sync performance significantly. Saving your precious time and bandwidth. For large file, it can reduce time of sync from hours to just seconds!

Side by Side Comparison
Intuitive side by side folder comparison lets you preview all actions before actual sync. You can see what exactly will happen before the files can be synchronized.

Scheduled Sync
Beyond Sync has built-in scheduler to let you schedule sync at a specified time. It can run as a Windows Service to keep your files in sync 7*24. It works in background, no user interaction is required. You can receive email notification when sync completes.

Main Features
Real Time Sync
Your files will be synchronized immediately when they are created, updated or deleted. It works in background, no user interaction is required.
Block Level Sync
Only copy changed part when a file is updated, not the whole file. ( ? )
Run as a Windows Service
Beyond Sync can run as a Windows Service to keep you files in sync 7*24 hours. No matter you logged in or not.
Synchronize network folders
You can synchronize folders with other computers easily.
High performance multiple threads file transferring
Synchronizes multiple files at the same time. You’ll get the best performance.
Handle different time zone
Synchronize files correctly even if the time zone between source and target is different.
Conflict detection
How about if you modified a same file in both source and target folder? Most software can NOT handle this, they simply overwrite old files. Beyond Sync takes care of this situation. You can ensure your files will not be overwritten by mistake!
Email notification
Notify you when something goes wrong. You can monitor the sync process anytime, anywhere.
Command Line mode is supported
You can integrate the sync process with your current workflow.
Byte-to-byte verification
Ensure your files were synchronized 100% successfully.
And much more.

Whats New
Updates: official site does not provide any info about changes in this version

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Beyond Sync 7.5.60.1394 Multilingual (7.9 MB)

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Omni Loop (2024) [720p] [WEBRip] [YTS MX]

Omni Loop (2024) 5.6 (3,348 Votes)
Runtime: 1h 52m

Genre: Drama, Sci-Fi

Cast: Mary-Louise Parker, Ayo Edebiri, Carlos Jacott

Plot: A woman from Miami, Florida decides to solve time travel in order to go back and be the person she always intended to.

Omni Loop (2024) [720p] [WEBRip] [YTS MX]

IMDB information:
Title: Omni Loop (2024)
Genres: Drama
Description: A woman from Miami, Florida decides to solve time travel in order to go back and be the person she always intended to.
Director: Bernardo Britto
Writer: Bernardo Britto
Actors: Mary-Louise Parker, Ayo Edebiri, Carlos Jacott
Rating: N/A
Runtime: 107 min
Language: English
Country: United States
Rate: N/A Click to expand…
IMDb:
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https://www.imdb.com/title/tt28150132/

mp4 | 1022.89 MB | 1280×534
01:51:23 | avc1 | Unknown language
1149 Kbps | 23.976 fps | 2.40:1 Click to expand…
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