Over the past decade, nanotechnology has revolutionized health and wellbeing, offering transformative solutions to challenges in medicine, biology, and environmental health. Leveraging the unique properties of nanoscale materials, researchers have advanced precision medicine, regenerative therapies, advanced diagnostics, and sustainable healthcare systems. This book celebrates 15 years of Nano LIFE by compiling 10 groundbreaking articles that exemplify the journal’s role in bridging nanotechnology and life sciences. The volume explores significant achievements in nanomedicine, such as multifunctional nanoparticles for targeted therapeutics and diagnostics, which have advanced cancer treatment, cardiovascular health, and neurodegenerative disease management. It also highlights the role of nanostructured biomaterials and electrospinning techniques in revolutionizing tissue engineering and regenerative medicine. Further, the book examines the impact of nanotechnology during global health crises like COVID-19, showcasing nanosensor-based diagnostics, accelerated vaccine development, and adaptive drug delivery systems. Fundamental research insights, including the biophysical properties of cancer cell surfaces and their therapeutic potential, are also discussed. This collection underscores the resilience and ingenuity of nanotechnology research, reflecting on its profound impact over the past 15 years and its potential to redefine the future of science and healthcare. An invaluable resource, it serves researchers, clinicians, and innovators aiming to harness nanotechnology for global health and wellbeing.
Contents:
- Electrospinning and Electrospraying with Cells for Applications in Biomanufacturing (Q Zhao and M Wang)
- COVID-19 Testing: Frequency Wins over Sensitivity in Control of Disease Transmission (F Berthiaume)
- Cancer Cell Surface Negative Charges: A Bio-Physical Manifestation of the Warburg Effect (D Shi)
- Therapeutic Delivery of Stromal Cell-Derived Factor-1 for Injury Repair (A Yeboah, M L Yarmush and F Berthiaume)
- Novel Brain-Derived Neurotrophic Factor Controlled-Release Formulation Promotes Neuroprotection In Vitro (I Perez, E Strauss, S Vyas, R S Schloss and M L Yarmush)
- A Review of Three Major Factors Controlling Carbon Nanotubes Synthesis from the Floating Catalyst Chemical Vapor Deposition (D R Chen, M Chitranshi, M Schulz and V Shanov)
- Gold Nanoparticles in Cancer Imaging and Therapeutics (H-C Huang, J Ramos, T S P Grandhi, T Potta and K Rege)
- Magnetic Nanoparticle Hyperthermia in Cancer Treatment (A J Giustini, A A Petryk, S M Cassim, J A Tate, I Baker and P J Hoopes)
- Sizes and Sufficient Quantities of MSC Microspheres for Intrathecal Injection to Modulate Inflammation in Spinal Cord Injury (S Kumar, J Babiarz, S Basak, J H Kim, J Barminko, A Gray, P Mendapara, R Schloss, M L Yarmush and M Grumet)
- Effect of the Organic Functionality on the Synthesis and Antimicrobial Activity of Silver Nanoparticles (P C Pandey, A K Tiwari, M K Gupta, G Pandey and R J Narayan)
- Quantification of Magnetic Nanoparticles in ex vivo Colorectal Lymph Nodes (L Molenaar, M M H van de Loosdrecht, L Alic, J van Baarlen, J J H J Meijerink, B ten Haken, I A M J Broeders and D J Lips)
- Intratumoral Photosensitizer Delivery and Photodynamic Therapy (C-H Ma, J Yang, J L Mueller and H-C Huang)
- Nanoparticles in Joint Arthroplasties (R J Thomson, A K Limberg and D W V Citters)
- Iron Oxide Nanoparticles for Tissue Repair and Regeneration (T Nanda, M Alobaid and K Rege)
- Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health (F He, X Wu and S Lin)
- Exploiting the Electrical Nature of Biofilms for Long-Term Monitoring of Quiescent Aquatic Environments via Open-Circuit Microbial Potentiometric Sensors: Evidence of Long-Distance Electrical Signaling (S R Burge, K D Hristovski, R G Burge, L Pejov, D Boscovic, E Taylor and D A Hoffman)
Readership: Researchers, academics, and professionals working in fields of nanotechnology, nanomedicine, biomedical engineering, materials science, and regenerative medicine; Graduate and post-graduate students studying advanced nanotechnology, nanomedicine, tissue engineering, and bioengineering; Professionals in academia and industry involved in drug delivery, cancer therapy, and diagnostics; Professionals in healthcare and pharmaceutical industries who are involved in developing nanomedicine-based therapies, diagnostic tools, and advanced materials.
Dr Donglu Shi is a Professor of Materials Science and Engineering at the University of Cincinnati’s College of Engineering. He served as the Chair and Graduate Director of the Materials Science and Engineering program from 2013 to 2023. Dr Shi’s research spans diverse fields, including nanoscience, energy materials, biomedical engineering, precision medicine, and condensed matter physics. His prolific work includes over 300 peer-reviewed journal publications, with many published in prestigious journals such as Nature, Physical Review Letters, Advanced Materials, Biomaterials, and ACS Nano. He has also authored 13 books on topics ranging from superconductivity and electronic materials to nanomedicine, magnetism, and biomaterials. Dr Shi is the co-editor-in-chief of Nano LIFE, serves on the editorial board of Biomaterials Advances, and is an associate editor for the Journal of Nanomaterials. His contributions have been recognized with numerous awards, including the George Rieveschl Jr. Award for Distinguished Scientific Research, the Sarah Grant Barber Outstanding Faculty Advisor Award, the Neil Wandmacher Teaching Award, the Distinguished Engineering Researcher Award, and the Sigma Xi Research Recognition Award. A Fellow of ASM International and a Graduate College Fellow at the University of Cincinnati, Dr Shi continues to make significant contributions to advancing materials science and engineering.Professor Martin L Yarmush is an internationally recognized bioengineer and translational scientist who has been a leader in the fields of tissue engineering and regenerative medicine, BioMEMS and nanotechnology, applied immunology and biotechnology, metabolic engineering, and medical device development. He currently serves as the Paul and Mary Monroe Endowed Chair and Distinguished Professor of Biomedical&Chemical Engineering at Rutgers University, and the Director of the Center for Engineering in Medicine and Surgery at the Massachusetts General Hospital (MGH). He has published over 580 refereed journal articles and over 60 patents&patent applications. He has also taught a spectrum of courses from molecular genetics, biochemistry, and immunology, thermodynamics and transport phenomena, to advanced biotechnology. Professor Yarmush is the recipient of over 30 local and national awards including Founding Fellow of AIMBE, Fellow of BMES, Fellow of the US National Academy of Inventors, and Fellow of the US National Academy of Engineering. He is also the founding editor-in-chief of the Annual Review of Biomedical Engineering and co-editor-in-chief of Nano LIFE. He has pioneered advancements in tissue engineering, stem cell therapies, bioartificial organs, organ storage methods for transplantation, and many more. Some of these innovations have led to patents and company formations, including Molecmo (later Novira), which developed novel antiviral drugs for Hepatitis B and was acquired by J&J in 2015 for $600M.
